Alexandra
Ikeguchi
MD
Education, Training, Board Certifications
- MD, Columbia University Physicians and Surgeons
- Residency, Internal Medicine, Columbia-Presbyterian Medical Center
- Fellowship, Hematology/Oncology, Columbia-Presbyterian Medical Center
- Internal Medicine, American Board of Internal Medicine
- Medical Oncology, American Board of Internal Medicine
- Hematology, American Board of Internal Medicine
Clinical Expertise
- Melanoma
- General medical oncology
Affiliations
Fred Hutch Cancer Center – Provider
PUBLICATIONS
RESEARCH AND/OR CLINICAL INTERESTS
From the time of her first exposure to research in the biologic sciences, Dr. Ikeguchi has been fascinated by the processes by which a single cell can divide and differentiate into organ systems with diverse functions. As a related concept, the pathology in this normal developmental process that ultimately leads to malignancy has been extremely interesting to her. As she proceeded through her education, Dr. Ikeguchi pursued this focus through specialty training in Hematology and Oncology and did her fellowship research in a basic science lab studying protein-protein interactions between the ABL oncoprotein and its regulator, ABI1. For family and personal reasons, she initially elected to start her career in pure clinical practice. Her years of direct patient care ultimately helped her progress towards her research goal in that they made her acutely aware of cancers for which established therapies are completely inadequate and in which development of new treatments will have the most impact. Dr. Ikeguchi therefore arrived at her present focus in the biology of melanoma, one of the cancers most resistant to standard chemotherapy.